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  • Feature Contributions to the World’s - Santen

    2017-3-31 · 18 Santen Pharmaceutical Co., Ltd. Annual Report 2017 27 % Contributions to the World’s ... Launched in 2002, the bottle design won a Good Design Award in 2008. Current Glaucoma Treatment and Santen’s Response to Therapeutic Needs ... single-dose formulation of Tapros currently available in Japan and Singapore, for which Santen is filing ...

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  • Medium-term Management Plan FY2011-2013 - Santen

    2017-1-18 · Santen Pharmaceutical Co., Ltd. Medium-term Management Plan FY2011-2013. 2 Santen’s Values ... Glaucoma Tapros/Taflotan DE-112 Adenosine A 2A Agonist Phase1/2 Development in Process Status Launched in ... Design an optimal global supply chain system from long term point of view.

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  • Preperimetric Glaucoma Prospective Observational

    2017-12-13 · Tafluprost ophthalmic solution 0.0015% (TAPROS ®; Santen Pharmaceutical, Osaka, Japan) is a selective prostaglandin F receptor agonist, and topical administration of tafluprost reduces IOP in glaucoma patients.

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  • Q3 FY2020 Results Follow-up -Outlook for Chinese ... -

    2021-2-9 · products, Tapros and Diquas. In addition to aggressively shifting to this area, in the medium term, I think we will accelerate the launch of new drugs to minimize the impact of VBP. In this context, activities with private hospitals will be strengthened in the short term. There are many patients who undergo surgery at their own expense.

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  • Q/A session (summary) (August 1, 2017) A1-1 - Santen

    2017-8-8 · the study design based on testing lower frequency and non-inferiority? A3-1 So, we are hoping that we can reduce dosing frequency by 50%. So, in other words, we will have to show at least numerical superiority. Less frequent dosing and non-inferior efficacy compared to four times a day. Q3-2 DE-117 is my second question.

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  • Business Review - Santen

    2019-9-26 · In the OTC pharmaceutical business, Santen continues to focus on sales of mainstay products such as the Sante FX and Soft Santear series. At the same time, Santen continues working to expand the availability of high-value, high-end brands including the Sante Medical series and the Sante Beautéye series. In December 2018, Santen

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  • Prospective Observational Post-Marketing Study of ...

    2017-5-13 · The aim of this study was to investigate the long-term intraocular pressure (IOP)-lowering effect and safety of tafluprost, a prostaglandin analogue, in actual clinical practice and to determine persistency of tafluprost as an indicator of its benefit–risk balance. This was a large-scale, post-marketing, multicenter, non-interventional, open-label, long-term study.

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  • Santen Vision 2030 - EuroTimes

    2020-10-1 · Implanted through a conjunctival/Tenon’s flap, MicroShunt is an 8.5mm tube that shunts aqueous from the anterior chamber through a 70-micron lumen into a filtration bleb. Fins on the tube help keep the shunt in place and prevent excess drainage around the device. Early multi-centre studies show mean IOP reduction of 30-to-55%, with success ...

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  • The signs of ocular-surface disorders after switching

    The signs of ocular-surface disorders after switching from latanoprost to tafluprost/timolol fixed combination: a prospective study Hideaki Okumichi,1 Yoshiaki Kiuchi,1 Tetsuya Baba,2 Takashi Kanamoto,3 Tomoko Naito,4,5 Shunsuke Nakakura,6 Hitoshi Tabuchi,6 Hiroki Nii,7 Chie Sueoka,7 Yosuke Sugimoto1,8 1Department of Ophthalmology and Visual Science, Graduate School of …

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  • Seasonal variation of intra-ocular pressure in

    2020-8-18 · A more powerful study design would involve measuring IOP in the same cohorts of glaucoma and non-glaucoma patients multiple times across the four …

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  • The clinical effectiveness of tafluprost on Japanese ...

    2018-3-20 · The inclusion criteria were as follows: 1) NTG diagnosis in at least one eye; 2) no treatment history with tafluprost (Tapros ® ophthalmic solution 0.0015%, preserved multidose, Santen Pharmaceutical Co., Ltd.); and 3) existence of visual field data measured with Humphrey perimeter (Humphrey Visual Field Analyzer, Carl Zeiss Meditec AG, Jena ...

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  • Summary of Consolidated Financial Results for the Nine ...

    2021-2-4 · Listed Company Name: Santen Pharmaceutical Co.,Ltd ... currently available to the Company and on certain assumptions deemed to be reasonable by the Company. Actual results may differ from these forecasts due to various factors. ... Tapros ophthalmic solution ¥7.0 billion (YoY -3.4%) ...

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  • Atomic Modulation, Structural Design, and Systematic ...

    2020-1-19 · Therefore, a new advanced descriptor with more reasonable accuracy is desired. 3 Design Principles for Electrocatalysts 3.1 Electrocatalytic Active Centers. Since dinitrogen adsorption/activation initiates electrochemical NRR, an effective electrocatalyst should primarily possess active sites/centers for the adsorption of dinitrogen molecules.

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  • Pharma Leader Series: Top 25 Ophthalmic Drug

    2014-3-3 · Assess product portfolios, other activities and revenue predictions to 2024:• Santen• Senju• ValeantYou find sales prospects for brands such as Hyalein, Tapros/Taflotan, Cravit, and Diquas ...

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  • Modeling Emerging Technologies using Machine

    Modeling Emerging Technologies using Machine Learning: Challenges and Opportunities Invited Talk Florian Klemme , Jannik Prinz , Victor M. van Santen , Jorg Henkel¨ , Hussam Amrouchy Karlsruhe Institute of Technology, fklemme, victor.santen, [email protected]

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  • Santen - An Overlooked Play On An Overlooked Space ...

    2017-3-10 · Santen holds over 40% share in Japan's ophthalmic drug market and is generating double-digit growth as the #2 player in China, and is one of three fully-diversified ophthalmic drug players.

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  • Royalty Rates for Pharmaceuticals & Biotechnology, 6th

    2012-7-18 · Company, predecessor to Pfizer, Inc., Centocor, Inc., Santen Incorporated and Hoffman-La Roche Inc. King acquired an exclusive license from Novavax on January 8, 2001 to promote, market, distribute and sell Estrasorb™, Novavax's topical, transdermal estrogen replacement therapy,

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  • Tuning the electrocatalysts for oxygen evolution

    2017-9-1 · Various types of carbon are widely used in the realm of electrochemistry as conventional electrodes. Although their overpotentials for OER are high, it is still reasonable to use carbon as a metal-free electrode for OER due to low cost and versatility in design , , , , , , , , , . For this purpose, it is vital to increase the active sites ...

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  • Metal‐Nitrogen‐Doped Carbon Materials as Highly

    ii) Design principle for coordination environment: The coordination environment of active centers, including coordination number and types of ligands, plays a key role in modulating the affinity of catalysts toward reactants and intermediates, the selectivity toward target reaction, and thus the catalytic performance of the M-N-C-based materials.

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  • Towards the computational design of solid catalysts ...

    2021-7-9 · Ethylene oxide synthesis. Ethylene oxide (EO) is an important chemical with an annual global production of the order of 10 million tons 73. It is primarily used in organic synthesis reactions. All ...

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  • Glaukos Corporation - Glaukos Expands its PRESERFLO ...

    2021-5-18 · Glaukos Corporation (NYSE: GKOS), an ophthalmic medical technology and pharmaceutical company focused on novel therapies for the treatment of glaucoma, corneal disorders and retinal diseases, today announced that it has entered into a new development and commercialization license agreement with Santen Pharmaceutical Co., Ltd. (Santen) for the PRESERFLO™ MicroShunt …

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  • Santen Group Corporate Profile - pharmacy.pusan.ac.kr

    Santen’s Values and Mission Statement *1 Santen’s original interpretation of a passage from chapter 22 of Zhongyong (The Doctrine of the Mean) by Confucius, meaning “exploring the secrets and mechanisms of nature in order to contribute to people’s health.” By focusing on ophthalmology, Santen …

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  • Density functional theory in surface chemistry and ...

    2021-5-11 · Shipping And Handling. UK. £3.00 2nd class delivery (4-5 working days) FREE over £35.00. £4.00 1st class (1-2 working days) £8.00 Special Delivery or APC overnight* (next working day) EU (selected countries) £5.00 (Ireland) by Royal Mail Tracked and Signed. All international (non UK) orders are typically delivered within 7-14 days, but can ...

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  • Santen Eyecare Terms And Conditions

    2019-5-25 · Investigation of the Effects of the Structure and Chelate Size of Bis-oxazoline Ligands in the Asymmetric Copper-Catalyzed Cyclopropanation of Olefins: Design of a New Class of Ligands. The Journal of Organic Chemistry 1997 , 62 (8) , 2518-2526.

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  • Asymmetric Diels-Alder reaction catalyzed by a chiral ...

    2021-2-17 · C–H bond activation in light alkanes: a theoretical perspective Y. Wang, P. Hu, J. Yang, Y. Zhu and D. Chen, Chem. Soc. Rev., 2021, 50, 4299 DOI: 10.1039/D0CS01262A This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct ...

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  • C–H bond activation in light alkanes: a theoretical ...

    2012-7-18 · Company, predecessor to Pfizer, Inc., Centocor, Inc., Santen Incorporated and Hoffman-La Roche Inc. King acquired an exclusive license from Novavax on January 8, 2001 to promote, market, distribute and sell Estrasorb™, Novavax's topical, transdermal estrogen replacement therapy,

    Get Price
  • Royalty Rates for Pharmaceuticals & Biotechnology, 6th

    2011-4-1 · The first being the indirect route where methanol (MeOH) reacts with the surface to form surface methoxy, and this surface methoxy reacts with MeOH to form DME. Step 1) Step 2) The second mechanism is the direct route, where two MeOH molecules interact with the surface to yield DME. But how do we know which (if any) of these reactions take place?

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  • Methanol to Olefins

    the classic experimental design literature (e.g., Anderson and McLean, 1974; Petersen, 1994; Snedecor and Cochran, 1989; Steel et al., 1997), the extra fixed effect parameters are eliminated by imposing sum-to-zero constraints. Effects for a main effect sum to zero. Effects for interactions sum to zero within each level of the component main ...

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  • Analysis of Combined Experiments Revisited

    2016-9-8 · UMIN-CTR 臨床試験登録情報の閲覧. IOP-lowering effect lasting for 24 hours of Tapcom combination ophthalmic solution switched from Tapros ophthalmic solution 0.0015% and Timoptol XE ophthalmic solution 0.5%. IOP-lowering effect lasting for 24 hours of Tapcom combination ophthalmic solution switched from Tapros ophthalmic solution 0 ...

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  • Think it, Build it, Shhhhip it! - Chalmers

    2020-7-3 · Entrepreneurship and Business Design . Think it, Build it, Shhhh...ip it! Managing trade secrets in the context of agile ... (specifically the contextual requirement of “reasonable steps”), it is possible to manage ... Sarah van Santen, for her invaluable guidance and feedback, and without whom this thesis would not have come ...

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  • Santen Group Corporate Profile - pharmacy.pusan.ac.kr

    Santen’s Values and Mission Statement *1 Santen’s original interpretation of a passage from chapter 22 of Zhongyong (The Doctrine of the Mean) by Confucius, meaning “exploring the secrets and mechanisms of nature in order to contribute to people’s health.” By focusing on ophthalmology, Santen …

    Get Price
  • Density functional theory in surface chemistry and ...

    2021-2-17 · C–H bond activation in light alkanes: a theoretical perspective Y. Wang, P. Hu, J. Yang, Y. Zhu and D. Chen, Chem. Soc. Rev., 2021, 50, 4299 DOI: 10.1039/D0CS01262A This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct ...

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  • C–H bond activation in light alkanes: a theoretical ...

    2019-10-25 · Considering that aging could be a confounding factor when the ocular biometry is determined, it is reasonable to design a research to minimize the effect of aging. A Medline search did not extract any studies reporting on the correlations between the degree of myopia and the biometrics of the anterior segment of the eye of younger Japanese ...

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  • Santen Eyecare Terms And Conditions

    van Santen & Bolleurs art direction | wendy van santen and hans bolleurs for the summer campaign of woord.nl Diy Design Design Art Interior Design Feast Of Love Van Santen Concrete Color We Will Rock You Diy Couture Still Life Art

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  • Refractive error and biometrics of anterior segment of ...

    The objective of this study is to analyse the relationship between secondary crash risk and traffic flow states and explore the contributing factors of secondary crashes in different traffic flow states. Crash data and traffic data were collected on the I-880 freeway in California from 2006 to 2011. The traffic flow states are categorised by three-phase traffic theory.

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  • art direction | wendy van santen and hans bolleurs for

    Recruitment status Completed Unique ID issued by UMIN UMIN000016052 Receipt No. R000018656 Scientific Title Efficacy of IOP reduction and safety of Tapcom combination ophthalmic solution switched from Tapros 0.0015% and Timoptol XE 0.5% ophthalmic

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  • Analysis of Freeway Secondary Crashes in Different

    2020-9-15 · Monitoring blood reflux during gonioscopy in glaucoma. Gonioscopy may offer a reasonable and cost-effective method to evaluate the function of the trabecular micro-bypass device post-implantation and it could help in adjusting the therapy after the surgery. Gonioscopy forms an essential part of the glaucoma evaluation, enabling the structure of ...

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  • Glaukos Corporation - Glaukos Expands its PRESERFLO ...

    2021-5-18 · Glaukos Corporation (NYSE: GKOS), an ophthalmic medical technology and pharmaceutical company focused on novel therapies for the treatment of glaucoma, corneal disorders and retinal diseases, today announced that it has entered into a new development and commercialization license agreement with Santen Pharmaceutical Co., Ltd. (Santen) for the PRESERFLO™ MicroShunt …

    Get Price
  • The clinical effectiveness of tafluprost on Japanese ...

    2018-3-20 · The inclusion criteria were as follows: 1) NTG diagnosis in at least one eye; 2) no treatment history with tafluprost (Tapros ® ophthalmic solution 0.0015%, preserved multidose, Santen Pharmaceutical Co., Ltd.); and 3) existence of visual field data measured with Humphrey perimeter (Humphrey Visual Field Analyzer, Carl Zeiss Meditec AG, Jena ...

    Get Price
  • n FEATURE STORY Houston, - boeing.com

    2007-12-11 · the design world, and BCA is already there,” Santen said. Boeing Houston engineers are now gaining that expertise to compete for future NASA business. In addition to this support of the 787 and P-8A programs, Santen said his team is looking for ways to help the Boeing Space and Intelligence Systems business unit in El Segundo, Calif.

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  • Perspective on the Martini model - Chemical Society ...

    The design of efficient, robust catalytic materials for the anodic evolution of oxygen in proton exchange membrane water electrolysers remains a great challenge to be overcome for the commercialisation of this promising hydrogen generating technology. In the present work, we demonstrate a simple, one-step or

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  • Organometallic chemical deposition of crystalline

    In breast adipose tissue, macrophages that encircle damaged adipocytes form “crown-like structures of breast” (CLS-B). Although CLS-B have been associated with breast cancer, their role in benign breast disease (BBD) and early carcinogenesis is not understood. We evaluated breast biopsies from three age-matched groups ( n = 86 each, mean age 55 years), including normal tissue donors of the ...

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  • Macrophagic “Crown-like Structures” Are Associated

    The design of registration trials (fixed combination vs each component from an untreated baseline) gives us clear information about what to expect when initiating therapy. For the fixed combinations containing timolol, the dosing is twice daily (that of timolol), although the indication for the other component (dorzolamide or brimonidine) is ...

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  • Self Hosted Video – Karen Santen

    2017-12-1 · Iron deficiency, with or without anemia, is extremely frequent worldwide, representing a major public health problem. Iron replacement therapy dates back to the seventeenth century, and has progressed relatively slowly until recently. Both oral and intravenous traditional iron formulations are known to be far from ideal, mainly because of tolerability and safety issues, respectively.

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  • Fixed Combinations - Glaucoma Today

    van Santen & Bolleurs art direction | wendy van santen and hans bolleurs for the summer campaign of woord.nl Diy Design Design Art Interior Design Feast Of Love Van Santen Concrete Color We Will Rock You Diy Couture Still Life Art

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